While Matteo Politano, Hirving Lozano, and Mario Rui were injured, Eljif Elmas was suspended, and the Partenopei were still aiming to surpass Maurizio Sarri's club record of 91 points. With Roberto Soriano and Adama Soumaoro on the treatment table and Riccardo Orsolini serving a suspension, the hosts were aiming for eighth place for potential European play.

As a result of his distraction from a strong push from Piotr Zielinski, Lukasz Skorupski gave the ball right to Victor Osimhen, who easily put it into the empty net for his 24th Serie A goal of the year. Andre Zambo, Frank While Osimhen sprang the offside trap to force a stop from Skorupski and Nico Dominguez blasted just wide from the outside of the box, Anguissa stung Skorupski's palms from a distance and Musa Barrow hammered across the face of goal.