The first leg of the quarterfinals was also played in the Conference League, but without representation of any Portuguese teams.

So far, Fiorentina (SC Braga's executioner in the competition) has the best tie, who thrashed Lech 4-1. Fiorentina, who achieved a categorical victory away, in Poland, reached the goals through the intermediary of the Brazilian Arthur Cabral (04 minutes), the Argentine Nicolás González (41), the Italian Giacomo Bonaventura (58) and the Frenchman Jonathan Ikone (63 ), while Lech Poznan saw Norwegian Kristoffer Velde score his only goal at 20.

In the other matches, there were draws between the Belgians from Gent and the English from West Ham (1-1), as well as in the clash between the Swiss from Basel and the French from Nice.