Second-half goals from Dusan Vlahovic and Weston McKennie were enough for Juve to inflict a seventh defeat in 10 matches on Pep Guardiola's struggling City who risk not reaching the last 16. English champions City languish in 22nd place in Europe's top club competition after having collected just eight points from their six matches in the revamped league phase.
That leaves City just one point above the bottom 12 places and elimination, with matches against Paris Saint-Germain and Club Brugge remaining, a position that would have been unthinkable at the start of the season. But City have unravelled in less than six weeks and are way off the pace both in the Premier League and Champions League thanks to just one win, over Nottingham Forest, since the end of October.