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Standing at 167 appearances for his country, it is a proud record for the former Captain of Spain's World Cup and European Championship tournaments, Iker Casillas.
Curiously, and as Marca pointed out, Ramos celebrated tying the record of his former colleague in the same stadium where he celebrated being awarded his 100th cap - in El Molinón of Gijón, back in 2013.
He is not far away from being the record apppearance holder in international football - with that distinction falling to Egypt's Ahmed Hassan.
Another record he is chasing is to become Spain's all time goalscoring defender. The centre back, from Camas nearby Sevilla, has 21 goals to his name - is just one away from Argentine Daniel Passarella, who scored 22 goals in 70 games during his career.
