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| Passing | CP/AT | YDS | TD | INT |
| Philip Rivers | 23/35 | 277 | 2 | 1 |
| Riley Leonard | 0/1 | 0 | 0 | 0 |
| Rushing | ATT | YDS | TD | LG |
| Jonathan Taylor | 16 | 46 | 1 | 7 |
| Tyler Goodson | 3 | 9 | 0 | 6 |
| Josh Downs | 1 | 3 | 0 | 3 |
| Receiving | REC | YDS | TD | LG |
| Josh Downs | 5 | 65 | 0 | 18 |
| Michael Pittman Jr. | 4 | 32 | 0 | 14 |
| Alec Pierce | 4 | 86 | 2 | 33 |
| Jonathan Taylor | 3 | 33 | 0 | 19 |
| Tyler Warren | 3 | 30 | 0 | 19 |
| Mo Alie-Cox | 2 | 16 | 0 | 8 |
| Ameer Abdullah | 1 | 4 | 0 | 4 |
| Andrew Ogletree | 1 | 11 | 0 | 11 |
| Fumbles | FUM | LOST | REC | YDS |
| Ameer Abdullah | 1 | 1 | 0 | 0 |
| Philip Rivers | 1 | 0 | 0 | 0 |
| Laiatu Latu | 0 | 0 | 0 | 0 |
| Kicking | FG | LG | XP | PTS |
| Blake Grupe | 2/2 | 51 | 3/3 | 9 |
| Punting | NO | AVG | I20 | LG |
| Rigoberto Sanchez | 0 | 50.5 | 1 | 54 |
| Kickoff Returns | NO | AVG | TD | LG |
| Coleman Owen | 3 | 29 | 0 | 33 |
| Tyler Goodson | 2 | 30 | 0 | 31 |
| Punt Returns | NO | AVG | TD | LG |
| Defense | T-A | SCK | INT | FF |
| Camryn Bynum | 7-2 | 0.0 | 0 | 0 |
| Germaine Pratt | 6-2 | 0.0 | 0 | 0 |
| Nick Cross | 6-3 | 0.0 | 0 | 0 |
| DeForest Buckner | 5-1 | 0.0 | 0 | 0 |
| Zaire Franklin | 4-2 | 0.0 | 0 | 0 |
| Samson Ebukam | 4-1 | 0.0 | 0 | 0 |
| Cameron Mitchell | 4-0 | 0.0 | 0 | 0 |
| Neville Gallimore | 3-0 | 0.0 | 0 | 0 |
| Kenny Moore | 3-1 | 0.0 | 0 | 0 |
| Mekhi Blackmon | 3-0 | 0.0 | 0 | 0 |
| Laiatu Latu | 3-1 | 1.0 | 0 | 1 |
| Johnathan Edwards | 3-1 | 0.0 | 0 | 0 |
| Grover Stewart | 2-1 | 0.0 | 0 | 0 |
| Kwity Paye | 2-1 | 0.0 | 0 | 0 |
| Tyquan Lewis | 1-1 | 0.0 | 0 | 0 |
| Eric Johnson | 1-0 | 0.0 | 0 | 0 |
| Passing | CP/AT | YDS | TD | INT |
| Brock Purdy | 25/34 | 295 | 5 | 1 |
| Rushing | ATT | YDS | TD | LG |
| Christian McCaffrey | 21 | 117 | 0 | 24 |
| Brian Robinson Jr. | 5 | 20 | 0 | 11 |
| Mac Jones | 3 | -3 | 0 | -1 |
| Brock Purdy | 2 | 11 | 0 | 9 |
| Receiving | REC | YDS | TD | LG |
| George Kittle | 7 | 115 | 1 | 26 |
| Christian McCaffrey | 6 | 29 | 2 | 10 |
| Jauan Jennings | 5 | 71 | 1 | 21 |
| Kendrick Bourne | 3 | 27 | 0 | 14 |
| Demarcus Robinson | 2 | 23 | 1 | 22 |
| Jake Tonges | 1 | 7 | 0 | 7 |
| Skyy Moore | 1 | 23 | 0 | 23 |
| Fumbles | FUM | LOST | REC | YDS |
| Brock Purdy | 1 | 0 | 0 | 0 |
| Alfred Collins | 0 | 0 | 0 | 0 |
| Kicking | FG | LG | XP | PTS |
| Eddy Piñeiro | 2/3 | 38 | 6/6 | 12 |
| Punting | NO | AVG | I20 | LG |
| Kickoff Returns | NO | AVG | TD | LG |
| Skyy Moore | 4 | 28 | 0 | 36 |
| Brian Robinson Jr. | 2 | 27 | 0 | 31 |
| Punt Returns | NO | AVG | TD | LG |
| Skyy Moore | 1 | 8 | 0 | 8 |
| Defense | T-A | SCK | INT | FF |
| Tatum Bethune | 9-5 | 0.0 | 0 | 0 |
| Malik Mustapha | 8-5 | 0.0 | 0 | 0 |
| Ji'Ayir Brown | 6-4 | 0.0 | 0 | 0 |
| Darrell Luter | 6-1 | 0.0 | 0 | 0 |
| Upton Stout | 6-3 | 0.0 | 0 | 0 |
| Deommodore Lenoir | 3-1 | 0.0 | 0 | 0 |
| Kalia Davis | 3-3 | 0.0 | 0 | 0 |
| Sam Okuayinonu | 3-2 | 0.0 | 0 | 0 |
| Keion White | 3-2 | 0.0 | 0 | 0 |
| Dee Winters | 3-2 | 0.0 | 0 | 0 |
| Eric Kendricks | 2-2 | 0.0 | 0 | 0 |
| Bryce Huff | 2-1 | 0.0 | 0 | 0 |
| Alfred Collins | 2-1 | 1.0 | 0 | 1 |
| Clelin Ferrell | 1-1 | 0.0 | 0 | 0 |
| Luke Gifford | 1-1 | 0.0 | 0 | 0 |
| C.J. West | 1-0 | 1.0 | 0 | 0 |
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