Ajax take on Benfica at the Estadio da Luz as they return to Lisbon, where Haller scored four times on his Champions League debut when the Dutch champions beat Sporting 5-1 along the road at the Jose Alvalade in September.
Ivory Coast international Haller went on to score 10 times in the group stage, becoming just the second player to find the net in all six group games in a Champions League campaign after Cristiano Ronaldo in 2017.
"Before the competition if you asked me if I would score that many goals of course I would say no," Haller told Ajax TV ahead of the knockout stages of Europe's elite club competition.
"I was happy with one already. I score one goal in the Champions League and my life is done.