After scoring 16 goals in their past three games, including a thrilling 3-3 draw with Juventus, La Dea was on a roll and getting ready for Tuesday's Coppa Italia quarterfinal matchup against Inter. Injuries to Davide Zappacosta and Jose Luis Palomino allowed Teun Koopmeiners to return from suspension. Ignacio Pussetto, Manuel De Luca, Andrea Conti, and Abdelhamid Sabiri joined them on the treatment table as the Blucerchiati remained in the drop zone. Sam Lammers made his debut for the opposition club.
Juan Musso made a last-ditch double stop on Manolo Gabbiadini from a tight angle and the Tommaso Augello follow-up as Samp had the initial opportunity. Harry Winks made a vital block on Ademola Lookman from six yards out before Hans Hateboer slipped in at the far post to turn a Jeremie Boga cross across from point blank range.