It will be similar to last season's CSL, when the 16 clubs were housed in two hotels, in two locations, and kept away from the public to prevent infections.
For the new campaign, half of the teams will be stationed for the first phase in the southern city of Guangzhou and the other half in Suzhou, near Shanghai.
Fabio Cannavaro's former champions Guangzhou will be based in their home city.
Shanghai Port, who boast the 60-million-euro Brazilian Oscar and former West Ham United striker Marko Arnautovic, will start the season in Suzhou.