Boca Juniors were crushed by a hat-trick by Athletico Paranaense's Marco Ruben in the Copa Libertadores. Last year's runners-up, Boca slumped to a 3-0 defeat to Athletico, who moved top in Group G, in Curitiba.
He became just the second player to score a hat-trick against Boca in the Libertadores, after Jose Castillo – for Bolivar in 2004.
In Buenos Aires, Palmeiras were handed their first defeat in Group F with a 1-0 loss to San Lorenzo. Junior were left point-less in the group after a 1-0 defeat at Melgar.
In Group D, San José and LDU Quito played out a thrilling 3-3 draw that featured three own goals.
Reigning champions River Plate dropped to third in Group A – albeit with a game in hand – after Palestino beat Alianza Lima 3-0.
Cerro Porteno retained their perfect record in Group E, thanks to a 1-0 victory at home to Nacional.