United will go top of the table if they avoid defeat against Burnley at Turf Moor on Tuesday, a feat that would make Sunday's showdown with reigning champions and bitter rivals Liverpool all the more mouthwatering.
De Gea was part of the last United side to win a championship as Alex Ferguson retired in a blaze of 2012-13 glory.
Since then, they have tended to exist on the margins of the Premier League's 'big six' and this is something the Spain goalkeeper is keen to change.
"Yes I have been fighting for the title in a couple of seasons when Sir Alex was here. Now we are there again and it’s taken us a lot of time to get there to be honest and we cannot miss this chance," De Gea told United's official website.