Julen Lopetegui's side have been linked with the Belgian U21 international in the past, but now Manchetser City and Barcelona are both now reported to be interested in a move for the 21-year old.
Lokonga is out of contract with Anderlecht in June 2020, and clubs outside Belgium are free to negotiate a pre-contract agreement with him from January.
However if any of the interested parties want to sign him before his contract expires, he is reported to be available for a fee of around €5M, according to reports in Marca.
Despite the reported interested in him, Lokonga has previously stated his preference to remain with Anderlecht, and sign a two year extension to his current deal at the club.