Centre back Nathan Ake had to be taken off early in the game with a muscle injury and will return to his club Manchester City immediately, missing the Netherlands’ Nations League games with Bosnia and Poland.
Right back Hans Hateboer meanwhile was brought off at halftime after clashing heads with Spain’s Jose Gaya, who had to be taken off immediately for Luis Enrique’s side.
“I don’t think this game needed to be played,” De Boer told a news conference.
“Money is very important but we also need to look after our players. All interested parties need to sit down and talk because the health of our players is important. We all agree about that, and decisions need to be made.”