Spinazzola was forced to pull out of the Italy squad after tests on Tuesday showed a problem with his right thigh.
The 24-year-old limped off during the match against Parma last weekend, but Gazzetta dello Sport reports he will be out for no more than 7-10 days with a slight strain to his flexor.
Therefore, he has ample time to recover before Roma resume their campaign on November 24 against Brescia and considering further challenges as for Europa League.