Giovanni van Bronckhorst's side are due to be at Fir Park on Sunday, 24 April but have asked if the game can be brought forward to the previous day.
Rangers play their first leg in Germany on 28 April, then visit Celtic on 1 May, before hosting Leipzig on 5 May. The SPFL are discussing the matter with Motherwell, Sky Sports and the police.
"Hopefully the SPFL is helping us to perform in Europe," Van Bronckhorst said.
"You have seen in other countries where a lot of games are moved, different dates or even kick-off times were changed. I think we are having talks now.
"We just want to do the best for Scotland; we are still involved in Europe and getting a lot of [co-efficient] points".