Zouma made the switch from Stamford Bridge to the London Stadium in a £29.8million deal in the summer after seven years and 151 appearances for Chelsea.
The Frenchman has made an impressive start in east London but knows to expect a tough afternoon against his former employers on Saturday.
“It will feel special in a way because I’ve been there for so many years," said Zouma.
“I want to beat Chelsea because I want to beat everybody. I play for West Ham now and I’m very happy to be here. It’s going to be a tough game as we know they have a lot of strength, but we have to use our strength to make them suffer.”