The previous record for most goals scored in an Eredivisie game was also held by Ajax when they beat Vitesse 12-1 in 1972.
Led by 19-year-old Lassina Traore, who scored five times and assisted three more, Ajax dominated the contest and were already 4-0 up when Venlo were reduced to 10 men after skipper Christian Kum was sent off on VAR review for a high boot.
What followed was an eight-goal salvo in 24 second half minutes as Ajax’s players controlled possession and lined up to take shots on goal, with veteran 37-year-old forward Klaas Jan Huntelaar also scoring twice in two minutes.
The visitors finished the match with an eye-watering 23 shots on target and could have scored more had Venlo goalkeeper Delano van Crooij not made 10 saves.