After Diego Simeone's side scored twice in the opening six minutes through Julian Alvarez and Antoine Griezmann, Barca raced through the gears in a high-octane performance. The superb Pedri Gonzalez pulled one back with Pau Cubarsi, Inigo Martinez and Robert Lewandowski going on to score for the Catalan giants. Marcos Llorente netted for Atletico before Alexander Sorloth struck in the 93rd minute to leave the tie perfectly poised ahead of the second leg at the Metropolitano stadium on April 2.
Hansi Flick left Barca's top goalscorer Lewandowski out of the starting line-up, with Ferran Torres taking his place in a false nine role. Simeone picked a strong side despite his side's extremely tricky fixture list, with this the first of three matches against Barca and a Champions League last 16 tie against Real Madrid on the horizon.