After finishing bottom of their group last season Atletico are desperate to progress and know they face a fierce battle at De Kuip in the Netherlands, with the hosts fighting to avoid elimination. Atletico lead Group E on eight points, one ahead of Lazio and two up on third-placed Feyenoord, and a win would send them through.
Griezmann, who scored a fine header against Mallorca to take Atletico third in La Liga on Saturday, is in superlative form. The French forward has nine goals in the Spanish top flight, only trailing the division's top goalscorer, Real Madrid's Jude Bellingham, and has netted four in four Champions League matches thus far.
He has eight goals and two assists in his last seven games for the club, across all competitions. Griezmann played the full 90 minutes against Mallorca with coach Diego Simeone unable to rest the forward.