Luis Enrique said the win at Rennes 1-4 would lift his team's spirits ahead of Tuesday's game against Premier League leaders Liverpool after the disappointing home defeat in the first leg.
"I think we'll be in the best possible shape for the Liverpool game. We've got nothing to lose. Our only objective is victory and that's what we're going for," the Spaniard told reporters.
"Football allows for surprises; it is true that we were down and sad after the (first-leg) game but as we have analysed the game and after beating Rennes, which is a difficult team, it makes us hopeful.
"I repeat, we have nothing to lose, which makes us a more dangerous team than we usually are."
Luis Enrique also placed his trust in PSG's tactical versatility and praised his players' strength of mind in their quest for titles this season.