Real Madrid were handed a quick rematch with Jose Mourinho's Benfica in the draw for the Champions League play-off round on Friday, while reigning European champions Paris Saint-Germain will face domestic rivals Monaco.
Elsewhere, Newcastle United will be strong favourites against surprise packages Qarabag of Azerbaijan, with the first leg to come in Baku.
Bodo/Glimt, Norwegian champions in four of the last six years, were also surprise qualifiers for this stage and have been rewarded with a tie against last season's runners-up Inter Milan.
Juventus will take on Galatasaray, while Atletico Madrid face Club Brugge. Borussia Dortmund play Atalanta and Bayer Leverkusen were drawn against Olympiacos.
The two-legged play-off ties will take place in February, with the winners advancing to the last 16 in March.