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"A match without spectators is really different and we have to be well prepared," Favre said in a press conference ahead of Saturday's home derby.
"It's a question of mentality, which is very important. You put in a pass or you shoot and no-one reacts, so we had to prepare for that and it's very good that we have a sports pyschologist involved."
Dortmund usually attract a crowd of around 82 000 spectators for a derby, generating an intimidating atmosphere at their Signal Iduna Park stadium.
The Bundesliga is set to become the first top European league to resume, albeit behind closed doors and under strict hygiene measures.
This will be the 156th derby between Dortmund and Schalke - who are located just 50 kilometres apart - since the rivalry started in 1925, but the first without fans.
