Champions Barcelona won all four times the teams were pitted against each other last season but in his first Clasico as Real Madrid coach, Xabi Alonso snapped that run. Kylian Mbappe, who later missed a penalty, fired Madrid in front and although Fermin Lopez levelled for the visitors at the Santiago Bernabeu, Bellingham netted a second for the hosts before half-time which proved decisive.
Barca playmaker Pedri was sent off in the final stages for a second yellow card as tensions spilled over in the Spanish capital. Madrid's victory means they have won nine of their opening 10 league games and Alonso's side proved against Barca they can triumph on the big occasion.
Hansi Flick's team were led on the touchline by his assistant Marcus Sorg, as the German coach was suspended following a red card last weekend as they scraped a victory over relegation-battling Girona.