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Jonathan David gave Lille an early lead on the night, putting the French club ahead in the tie after last week's 1-1 first-leg draw. However, Emre Can squared things by converting a doubtful penalty for Dortmund on 54 minutes, and Maximilian Beier then fired in a fine winner for last season's runners-up.
Dortmund will now face Barcelona in the quarter-finals next month, having already lost 3-2 at home to the Catalans during the league phase in December. The result is a huge boost for Dortmund and their recently-appointed coach Niko Kovac, coming as the club languishes in 10th place in the Bundesliga.
It is a massive disappointment for Lille, who were hoping to reach the quarter-finals of the Champions League for the first time in their history after an outstanding performance during the league phase.
